Friday, December 01, 2006

Test Strips For The Rapid Detection Of Cocaine

Medical News Today

Saving the life of a poisoning victim is often a matter of minutes. It is best when the emergency doctor can perform a reliable diagnosis on the spot to determine which poison or what type of drug overdose a patient is suffering from. Complicated laboratory analyses and a complex apparatus are out of place in the emergency room. A team at the University of Illinois in Urbana has now laid the foundation for a new generation of rapid diagnostic tests that are as easy to handle as a pregnancy test: just dunk them in the sample and see if a colored band appears. These test strips are as reliable as laboratory methods. As a prototype, the researchers led by Yi Lu developed a test strip for the detection of cocaine in biological samples such as saliva, urine, and blood serum.

"Our method is based on tiny gold spheres and aptamers," reports Lu. Aptamers are single-stranded nucleic acid molecules that bind to certain target molecules with the same strength and specificity as antibodies. From a large number of DNA strands with random sequences (a library), it is basically possible to find a suitable aptamer for almost every target molecule. Says Lu: "The broad practical application of aptamers has thus far not realized its promise in practical diagnostics because the corresponding tests could not be made sufficiently user-friendly for the average user, who has not had laboratory training."

The new test strips for cocaine are different. When the end of the strip is dipped into a sample, the liquid travels along the strip to reach a zone with small gold-aptamer clumps. The trick lies in the special structure of these clumps: they are aggregates of nanoscopic gold spheres coupled to short DNA strands, some containing the biomolecule biotin. The DNA sequences are complementary to two regions of the cocaine-specific DNA aptamer. The aptamers bind to these strands, linking the gold spheres into larger aggregates. When the cocaine-containing liquid reaches these aggregates, the cocaine molecule instantly binds to the aptamers and removes them from the network; the aggregates fall apart into individual gold spheres. These free spheres are red. When the liquid travels further along the strip, it reaches a membrane. While the larger gold aggregates are stopped by the membrane, the red gold spheres are small enough to pass through it. They end up stuck to a narrow strip of streptavidin, a biomolecule that grabs onto the biotin on the gold surface like a hook onto an eye. The gold spheres get concentrated on the narrow strip and become visible as a distinct red stripe on the test strip.

"Our method is universal," stresses Lu. "Based on this principle, we should be able to develop rapid tests for the emergency diagnosis of a large number of drugs and poisons, as well as physiological molecules. The same method is also applicable to environmental monitoring."

11 Comments:

Anonymous Anonymous said...

As a recovering addict I found this post very informative. I can tell you that addiction therapy is necessary if you want to get sober and stay sober.

2/27/2011 12:18:00 AM  
Blogger admin said...

Buy medicine With or Without your RX online. When you become a valued Customer of our Pharmacy, you no longer have to worry about looking elsewhere . We Now Do Offer Secure Packaging And Stealth Shipping / drop off depending on location

Where To Buy Painkillers And Anti-Anxiety Pills Without Prescription Online - Oxycodone For Sale | Vyvanse For Sale - Adderall For Sale - Concerta For Sale

Contact us Securely : keys2pharm {AT} gmail (.)com Or Wickr me ID: { keys2pharm }

We Offer A Full Refunds On Any Package That Does Not Make It To Its Destination.- Offer Safe And Discreet Overnight Shipping (24/H) To Clients Depending On Location. -Finest And Fast Services To All Our Clients, And We Make Sure They Are Treated Like Family.

{ BITCOINS PAYMENT{s} ONLY }

ADDERALL, XANAX, OXYCODONE, RITALIN, REVLIMID, ROXICODONE, OPANA, DILAUDID, SUBUTEX, CONCERTA, FENTANYL, METHADONE, Seroquel , HYDROCODONE, OXYCONTIN 80mg {OC}, QUAALUDES, SOMA, AND MORE

8/14/2019 12:21:00 AM  
Blogger topley said...

Money Transfer Service

Bank Transfers / Western Union Transfer / Wire Transfer / Bank Logins / PayPal Transfer / Money Gram are now available to the following countries :

USA, UK, EU, Canada, Australia, Russia, Netherlands, China, Malaysia, France, Thailand, Ukraine, Nigeria

Our Services for Worldwide and we exclusively deal with Western Union / Money Transfer / Bank Logins / CVV, Fullz / Money Gram. The global nature of our service enables us to interact with clients all over the world who have access to our services. Our proxy dealers process your transfer request(s) and we subsequently provide you with the details of your transfers the transactions are carried out in 1-2 hours. Our services are available 24/7/365 we strive to build a strong relationship with our clients.

Services We Provide to our valuable Clients:

Bitcoin Transfer
Wire Bank Transfer
Paypal Transfer
Western Union Transfer
Skrill Transfer
Carding
Credit Card (cc) for sale
Random CC for sale
Fullz for sale
Bank logins with High Balance selling
Teaching
GMAIL / Facebook
Whatsapp / Instagram

We also teaching all type of Hacking within a few days.
We are providing our work then make a deal.
Only serious / needy people contact us.

Support 24/7

Email - topley994@gmail.com

8/19/2019 06:26:00 PM  
Anonymous Anonymous said...

Are you interested in any kinds of hacking services?
Feel free to contact TECHNECHHACKS.

For years now we’ve helped so many organizations and companies in hacking services.
TECHNECHHACKS is a team of certified hackers that has their own specialty and they are five star rated hackers.

We give out jobs to hackers (gurus only) to those willing to work, with or without a degree, to speed up the availability of time given to jobs!!

Thus an online binary decoding exam will be set for those who needs employment under the teams establishment.


we deal with the total functioning of sites like,


• SOCIAL MEDIA (Facebook, Twitter, Instagram, Snapchat, google hangout etc.)

• SCHOOL GRADES

• IOS/OS

• CREDIT SCORES

• BANK ACCOUNTS

• SPOUSES PHONE

Our special agents are five star rated agents that specializes in the following, and will specially be assigned to you for a special job well DONE.

• WESTERN UNION TRANSFER

• CREDIT CARDS INSTALLATION

• MONEY FLIPPING

• CRIMINAL RECORDS

• BTC RECOVERY

• BTC MINING

• BTC INVESTMENT

Thus bewere of scammers because most persons are been scammed and they ended up getting all solutions to their cyber bullies and attacks by US.

I am Jason williams one of the leading hack agent.

PURPOSE IS TO GET YOUR JOBS DONE AT EXACTLY NEEDED TIME REQUESTED!!!



And our WORK SUCCESS IS 100%!!!



We’re always available for you when you need help.

Contact or write us on:

Technechhacks@gmail.com

SIGNED....!

Jason. W

TECHNECHHACKS
2021©️All Right Reserved

1/27/2021 03:39:00 PM  
Anonymous Anonymous said...

Are you interested in any kinds of hacking services?
Feel free to contact TECHNECHHACKS.

For years now we’ve helped so many organizations and companies in hacking services.
TECHNECHHACKS is a team of certified hackers that has their own specialty and they are five star rated hackers.

We give out jobs to hackers (gurus only) to those willing to work, with or without a degree, to speed up the availability of time given to jobs!!

Thus an online binary decoding exam will be set for those who needs employment under the teams establishment.


we deal with the total functioning of sites like,


• SOCIAL MEDIA (Facebook, Twitter, Instagram, Snapchat, google hangout etc.)

• SCHOOL GRADES

• IOS/OS

• CREDIT SCORES

• BANK ACCOUNTS

• SPOUSES PHONE

Our special agents are five star rated agents that specializes in the following, and will specially be assigned to you for a special job well DONE.

• WESTERN UNION TRANSFER

• CREDIT CARDS INSTALLATION

• MONEY FLIPPING

• CRIMINAL RECORDS

• BTC RECOVERY

• BTC MINING

• BTC INVESTMENT

Thus bewere of scammers because most persons are been scammed and they ended up getting all solutions to their cyber bullies and attacks by US.

I am Jason williams one of the leading hack agent.

PURPOSE IS TO GET YOUR JOBS DONE AT EXACTLY NEEDED TIME REQUESTED!!!



And our WORK SUCCESS IS 100%!!!



We’re always available for you when you need help.

Contact or write us on:

Technechhacks@gmail.com

SIGNED....!

Jason. W

TECHNECHHACKS
2021©️All Right Reserved

1/27/2021 09:50:00 PM  
Anonymous Studylivezone said...

I am looking for some good blog sites for studying. I was searching over search engines and found your blog site on imt cdl finance project synopsis. Well i like your high quality blog site design plus your posting abilities. Keep doing it.

11/09/2021 08:09:00 PM  
Blogger SixD Engineering Solutions Pvt Ltd said...

This is most informative and also this post most user friendly and super navigation to all posts.
3D Scanning Services
3D Scanning Reverse Engineering
Reverse Engineering Services

11/25/2021 04:27:00 AM  
Anonymous Amino Acids said...

Thanks for the post it was very informative. Britzone Amino acid supplementation may benefit you if your body is lacking in one or more of the essential amino acids. Buy Authentic Fitness & supplements.

12/04/2021 12:15:00 AM  
Blogger Robots At Your Service said...


Robotic Process Automation with no development

12/16/2021 07:15:00 AM  
Anonymous Studylivezone said...

I am looking for some good blog sites for studying. I was searching over search engines and found your blog site on Nmims solved assignment. Well i like your high quality blog site design plus your posting abilities. Keep doing it.

2/13/2022 09:58:00 PM  
Blogger Lock Your Blog said...


Hii,

What a fantastic article you have written, each word on this blog is fabulous. It's extremely strange how one can simply post helpful and well-written content for nothing. It's awesome to contribute informational information for free. I also want to share some crucial information with everyone in return for Lock Your Trip has suddenly launched some amazing. These tour packages have been made by professional travel agents who have years of experience. They have taken care of every important thing in the itinerary so that you can have an amazing traditional experience in India. So what are you waiting for, book Lock Your Trip now and leave for a memorable trip of your life.

Thank You

6/08/2023 03:23:00 AM  

Post a Comment

<< Home